BEGIN:VCALENDAR
VERSION:2.0
PRODID:icalendar-ruby
CALSCALE:GREGORIAN
X-WR-CALNAME:Cellular & Integrative Physiology Seminar – Yi Zhang\, PhD
X-WR-TIMEZONE:Central Time (US & Canada)
BEGIN:VEVENT
DTSTAMP:20260713T152538Z
UID:tag:localist.com\,2008:EventInstance_49860798483931
DTSTART:20251208T180000Z
DTEND:20251208T190000Z
DESCRIPTION:Yi Zhang\, PhD\n\nFred Rosen Professor\n\nDepts. of Genetics & 
 Pediatrics\n\nBoston Children’s Hospital & Harvard Medical Institute\n\n
 Title: “Targeted depletion of dysfunctional HSCs alleviates aging-relate
 d defects”Summary:  Aging is a process accompanied by functional decline
  in tissues and organs with great social and medical consequences. Develop
 ing effective anti-aging strategies is of great significance. Single cell 
 transcriptome analyses revealed that while HSCs in young mice are homogeno
 us\, those from old mice are molecularly and functionally heterogenous. Im
 portantly\, the functionally defective HSCs prevent functional ones from f
 unctioning. Targeted depletion of the dysfunctional HSCs alleviates aging 
 related functional decline in aged mice\, suggesting that rather than look
 ing for magic factors in young\, removing dysfunctional cells could be an 
 alternative for rejuvenation.  Ongoing work on how some of the HSCs become
  bad during aging will also be discussed.
GEO:29.50747;-98.575365
LOCATION:Long School of Medicine Building at Joe R. & Teresa Lozano Long Ca
 mpus\, LSOM 444B
SUMMARY:Cellular & Integrative Physiology Seminar – Yi Zhang\, PhD
URL;VALUE=URI:https://events.uthscsa.edu/event/cellular-integrative-physiol
 ogy-seminar-yi-zhang-phd
CATEGORIES:Lectures & Seminars
END:VEVENT
END:VCALENDAR