7703 Floyd Curl Drive San Antonio, TX 78229

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Hind Lal, PhD
Associate Professor of Medicine
The University of Alabama at Birmingham

Title: “Novel Mechanisms of Cardiac Function and Dysfunction”

Summary: Heart failure (HF) is a major public health problem worldwide. Dr. Lal's lab aims to elucidate the novel mechanisms of cardiac function/dysfunction and apply this knowledge to develop innovative strategies to prevent or treat HF. His well-established vertically integrated research program has demonstrated a strong track record of successfully conducting innovative and translational studies.

The ongoing strategic themes of investigations are: 1) define the mechanism of cancer therapeutic kinase inhibitors (KIs) mediated cardiotoxicity (cardio-oncology), and 2) delineate the inflammation axis of myocardial fibrosis in the diseased heart.

During these investigations, excessive activation of the fibro-inflammatory axis has emerged as a common mechanistic basis of cardiac pathologies in multiple settings.

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