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After a transformative 23-year legacy led by Professor Lawrence B. Harkless, The Diabetic Foot Update (DFUpdate) returns in 2025—revived, reimagined, and more vital than ever. Set once again in San Antonio, this iconic meeting honors the spirit of the original while embracing a bold new era of multidisciplinary collaboration, innovation, and limb preservation. Spearheaded by the American Limb Preservation Society (ALPS), DFUpdate 2025 shines a spotlight on one of the most complex and often overlooked complications of diabetes: the Charcot foot. This timely focus coincides with the 200th birthday of Professor Jean-Martin Charcot and represents a call to action for the global medical community.

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